Introduction to the issue regarding research regarding age related macular degeneration
نویسندگان
چکیده
منابع مشابه
the genetics of age-related macular degeneration
age-related macular degeneration (amd) is the leading cause of blindness in old subjects. it is a multifactorial disease with both environmental and genetic factors playing some role in its pathogenesis. similar to many other genetic diseases, the inheritance pattern of amd does not fit into simple mendelian rules. these diseases are caused by the presence of multiple genetic factors and are ca...
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Abstract Background: Transpupillary thermotherapy is a new treatment for subfoveal choroidal neovascularization which needs further evaluation. This study was aimed to evaluate the efficacy of transpupillary thermotherapy on regression of occult subfoveal choroidal neovascularization with or without pigment epithelial detachment in patients with age-related macular degeneration. Methods: In a ...
متن کاملبررسی اثر چندشکلی ژنتیکی xrcc7 با ریسک ابتلا به بیماریamd age-related macular degeneration))
amd بیماری تحلیل شبکیه است که عامل اصلی کوری در افراد بالای 55 سال در جهان غرب به شمار می-رود. در اثر این بیماری، لیپوپروتئین ها در شبکیه تجمع پیدا کرده و رگ زایی القاء می شود. ثابت شده است که عوامل ژنوتوکسیک محیطی مثل سیگار کشیدن، رژیم غذایی و نور در افراد پیر با زمینه ی ژنتیکی مستعد در بروز بیماری دخیل می باشند. بنابراین ما یک مطالعه ی مـورد- شاهـدی را ترتیب دادیم که شـامل 112 فرد مبتلا به am...
Association of Apolipoprotein E Alleles with Susceptibility to Age-Related Macular Degeneration in Iranian Patients
Background: We aimed here to investigate the association between alleles and genotypes of APOE and Age-related macular degeneration (AMD) development. Materials and Methods: After ophthalmological examination, 120 patients with confirmed AMD and 120 healthy controls were enrolled in the study. The polymorphic segment of APOE gene was PCR-amplified and sequenced to determine the frequency distr...
متن کاملage-related macular degeneration: a scientometric analysis
age-related macular degeneration (armd) is a major cause of central blindness among working aged adults across the world. systematic research planning on any subject, including armd is in need of solid data regarding previous efforts in this field and to identify the gaps in the research. this study aimed to elucidate the most important trends, directions, and gap in this subject. the data extr...
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ژورنال
عنوان ژورنال: Molecular Aspects of Medicine
سال: 2012
ISSN: 0098-2997
DOI: 10.1016/j.mam.2012.04.002